Free shipping on orders over $50 90-day money-back guarantee 14,134+ five-star reviews
Since 1984 · Doctor-designed nutrition

Bring your
edge back.

VitalFactors is the daily effervescent drink that restores NAD+ and supports natural HGH — the two fuels your body quietly loses after 40. Forty years of nutrition science. One glass. Every morning.

4.8 · 14,134+ customers
  • ✓ 90-day money-back
  • ✓ Cancel anytime
  • ✓ Free US shipping $50+
As featured on
What's inside

One glass. Everything that matters.

Every serving carries the two biological fuels your body quietly loses after 40 — plus a complete vitamin and mineral base. No caffeine. No sugar. No proprietary blends.

Why MDR

Forty years of nutrition science
in every bottle.

We don't ride trends. Every MDR formula is designed by doctors, built on peer-reviewed research, and guaranteed for 90 days.

Doctor-designed

Formulated by physicians and nutrition scientists — not marketers. Real doses, no proprietary blends.

40 years of research

At the front of nutrition science since 1984 — the same formulas tens of thousands have trusted for decades.

90-day guarantee

Don't feel the difference in 90 days? Full refund, no form, no questions. We stand behind every bottle.

The science

Your body's two master
fuels disappear after 40.

By midlife, NAD+ and human growth hormone decline sharply. That's why you feel slower, tire faster, and recover less. VitalFactors helps restore both.

  • Clean cellular energy
  • Strength & muscle tone
  • Sharper focus
  • Cardiovascular support
  • Youthful skin
  • Libido & drive

1 Massudi et al., PLoS ONE 2012.   2 Corpas, Harman & Blackman, Endocr Rev 1993.

−0%
NAD+ by age 401
−0%
HGH production by age 602
0+
Customers feeling the shift
Chris Cuomo

"Fitness and nutrition unite for a vibrant, healthy lifestyle. That's why I take Vital Factors as my favorite natural energizer."

The flagship lineup

Three formulas.
Forty years of results.

VitalFactors restores what time takes away. Fitness Tabs build your daily foundation. Start with one, or stack them.

Flagship · Bestseller
VitalFactors effervescent drink

VitalFactors

Daily NAD+ & HGH support · 40 effervescent tablets

4.8 (14,134)
$89/mo or $99 one-time
See the science →

Browse the full catalog →

Real customers

People who moved the needle.

"I recommend MDR to my patients who want a clean, physician-designed stack — nothing flashy, just dosed correctly."

Dr. Russell Smith, MDEmergency Medicine

"My clients over 45 use VitalFactors to recover faster and hold their strength gains. It just works."

Nick MurthaOwner, Catalyst Fitness · Fort Lauderdale

"I've been performing for six decades. VitalFactors keeps me feeling like I've got another six in me."

Pat BooneLegendary Singer & Film Star

"Nothing hidden. The full panel is on the label and I can look up every ingredient. That's rare in this industry."

Sandra K.Verified subscriber · 2 years

"Ninety days later I feel the difference in my recovery and focus. The guarantee made it risk-free to try."

Marcus T.Verified subscriber · 14 months
Subscribe & save

Save 10%. Free shipping.
Cancel any time.

Most customers subscribe — it's cheaper per month, you never run out, and you can skip, pause, or cancel in one click from your account.

Start a subscription
Questions

Before you start.

How quickly will I feel something?

Most customers report more consistent energy and better sleep within the first 2–3 weeks. Visible strength, skin, and endurance changes typically show up between weeks 6 and 12. Consistency matters more than dose — that's why we designed VitalFactors as a daily drink rather than a capsule stack.

What's actually in it?

VitalFactors is built around precursors for NAD+ (including nicotinamide riboside and niacinamide), amino acids that support natural HGH (arginine, ornithine, glutamine, glycine, lysine), plus key vitamins and minerals. Full Supplement Facts are on every bottle and on the product page.

Can I take this with my prescriptions?

MDR formulas are food-grade nutritional supplements, but any new supplement can interact with medications — especially blood thinners, blood-pressure medication, and diabetes medication. Bring the Supplement Facts panel to your doctor before adding it, and we'll honor the 90-day guarantee if your physician recommends you stop.

What's the subscription commitment?

Nothing beyond the current month. Skip a shipment, change the frequency, or cancel entirely from your account page in one click — or email us and we'll do it for you. No phone tree, no retention scripts.

How does the 90-day guarantee work?

Try any MDR product for 90 days. If you don't feel a measurable difference, send what's left back and we'll refund your full purchase — shipping included. No form to fill, no questions required.

Is this evaluated by the FDA?

These statements have not been evaluated by the Food and Drug Administration. Our products are not intended to diagnose, treat, cure, or prevent any disease. We publish our sources so you can check the research yourself.

Join 14,134+ people who already
feel the difference.

Start with VitalFactors

90-day money-back · Cancel anytime · Free US shipping $50+

Try VitalFactors — $89/mo